Do not break, crush, or chew it. Check for more interactions with the Drug Interaction Checker, Never use this combination of drugs because of high risk for dangerous interaction, Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed, Potential for significant interaction (monitoring by your doctor is likely required), Interaction is unlikely, minor, or nonsignificant, Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locator Tool Including 24 Hour, Pharmacies. Ask your pharmacist about using those products safely. font-size: medium; If you miss a dose, take it as soon as you remember if it is still near bedtime and you have trouble falling asleep. Anaphylaxis can be life-threatening and requires immediate medical attention. Publication types Clinical Trial Comparative Study Controlled Clinical Trial Make sure you tell your doctor if you have any other medical problems, especially: There is a problem with Of the total drug interactions, eCollection 2018. Combining antidepressants is a recognised step for those failing to respond to monotherapy. All rights reserved. Symptoms of overdose may include: extreme drowsiness, hallucinations, fast/irregular heartbeat, fainting, slow/shallow breathing, seizures. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). In general, you should avoid or limit the use of alcohol while being treated with buPROPion. Copyright: Merative US L.P. 1973, 2023. Consult your doctor for more details. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away. The results of some tests may be affected by this medicine. Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This report displays the potential drug interactions for the following 2 drugs: Applies to: Wellbutrin (bupropion) and doxepin. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The following information includes only the average doses of this medicine. This may cause headaches, dizziness, or blurred vision. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Food Interactions. Set a target date to quit smoking during your second week of treatment. Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. Mayo Clinic does not endorse any of the third party products and services advertised. It is very important that you receive only one prescription at a time for bupropion. Avoid combinations; the risk of the interaction outweighs the benefit. Also, you may experience symptoms such as mood swings, headache, and tiredness. Naltrexone is in a class of medications called opiate antagonists. In Canada - Call your doctor for medical advice about side effects. These side effects may go away during treatment as your body adjusts to the medicine. Do not share this medication with others. Sign in to your account to save this drug interaction list. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. Make sure you tell your doctor if you have any other medical problems, especially: Take this medicine only as directed by your doctor. Should I avoid certain foods while taking doxepin oral? Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. However, the dose is usually not more than 522 mg per day. Otherwise, call a poison control center right away. Find everything you need to know about Doxepin (Silenor), including what it is used for, warnings, reviews, side effects, and interactions. For this medicine, the following should be considered: Allergies CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. AdultsAt first, 100 milligrams (mg) two times per day. A double-blind controlled study comparing the effects of bupropion to doxepin in outpatients with primary depression was conducted to evaluate efficacy and safety differences between the two drugs. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. If you are a Mayo Clinic patient, this could Do not drive, use machinery, or do anything that needs alertness until you can do it safely. information and will only use or disclose that information as set forth in our notice of This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Your doctor may adjust your dose as needed. . However, children are more sensitive to the effects of this medicine than adults when used for treating depression. It is helpful to keep a list of all your current medications in your wallet or another location where it is easily retrieved. (See Additional Information for Healthcare Professionals). May make these conditions worse. All rights reserved. Wharton S, Raiber L, Serodio KJ, Lee J, Christensen RA. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Side effects reported during combination treatment were nausea (n = 2), dry mouth (n = 2), jitteriness/agitation (n = 2), fatigue/drowsiness (n = 2), increased blood pressure (n = 1), increased sweating (n = 1), insomnia (n = 1), pruritus (n = 1), headache (n = 1), sexual dysfunction (n = 1), and weight gain (n = 1). It is believed that when linezolid is given to patients taking serotonergic psychiatric medications, high levels of serotonin can build up in the brain, causing toxicity. Following a 7-day placebo washout period, patients could be treated for up to 13 weeks on either treatment. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Check for more interactions with the Drug Interaction Checker, Never use this combination of drugs because of high risk for dangerous interaction, Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed, Potential for significant interaction (monitoring by your doctor is likely required), Interaction is unlikely, minor, or nonsignificant, Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locator Tool Including 24 Hour, Pharmacies. Adderall (amphetamine / dextroamphetamine), Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, Drug class: miscellaneous anxiolytics, sedatives and hypnotics. Ask your doctor when to start or stop taking this medication. If you are prone to frequent or excessive alcohol use, talk to your doctor before starting buPROPion. You might need to measure your blood pressure at home. Serious Interactions These medications may interact and cause very harmful effects. Review of placebo-controlled trials with bupropion. Clinicians should strive to use antipsychotics or antidepressants with a lower risk of QTc prolongation in patients with multiple risk factors for this adverse event. 10. Click here for an email preview. There are 27 disease interactions with doxepin which include: depression anticholinergic effects anticholinergic effects cardiovascular disease pheochromocytoma acute myocardial infarction recovery cardiovascular disease depression seizure disorders glaucoma liver disease renal/liver disease bipolar screening bone marrow suppression diabetes Alcohol or marijuana (cannabis) can make you more drowsy. The molecular pathophysiology of depression and the new therapeutics. Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems, breathing problems, liver problems, recent heart attack, problems urinating (such as due to enlarged prostate), overactive thyroid (hyperthyroidism), personal or family history of glaucoma (angle-closure type), personal or family history of mental/mood conditions (such as bipolar disorder, psychosis), family history of suicide, seizures, conditions that may increase your risk of seizures (such as other brain disease, alcohol/sedative withdrawal). Rarely, after taking this drug, people have gotten out of bed and driven vehicles while not fully awake ("sleep-driving"). However, many patients experiencing depression are. and can have potentially adverse consequences. This survey is being conducted by the WebMD marketing sciences department. Get medical help right away if you have any very serious side effects, including: severe dizziness, fast/irregular heartbeat, fainting, seizures, eye pain/swelling/redness, widened pupils, vision changes (such as seeing rainbows around lights at night). An official website of the United States government. Since untreated mental/mood problems (such as depression, anxiety) can be a serious condition, do not stop using this medication unless directed by your doctor. Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine. Automatically receive FDA alerts, drug interaction warnings, plus data on food, allergy & condition interactions. Does doxepin oral interact with other drugs you are taking? Tables -Psychiatric medications with serotonergic activity, Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs), The FDA has issued new information about this safety issue, see the, An official website of the United States government, : Store at room temperature away from light and moisture. Your doctor may need to check your weight on a regular basis. Despite the limited evidence base, this strategy is widely used by clinicians in practice. drug interactions checker>bupropion hcl oral and doxepin oral interactions. To prevent constipation, eat dietary fiber, drink enough water, and exercise. Do not stop using any medications without first talking to your doctor. These could be symptoms of a serious liver problem. Check with your doctor immediately if any of the following side effects occur: Get emergency help immediately if any of the following symptoms of overdose occur: Some side effects may occur that usually do not need medical attention. Do not increase your dose or use this drug more often or for longer than prescribed. These drugs include cimetidine, St. John's Wort, drugs to treat irregular heart rate (such as quinidine/propafenone/flecainide), antidepressants (such as SSRIs including paroxetine/fluoxetine/fluvoxamine). Appropriate studies have not been performed on the relationship of age to the effects of bupropion in the pediatric population. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. Your list includes two medicines belonging to the 'antidepressants' category: Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Drug interactions between linezolid and selective serotonin reuptake inhibitors: case report involving sertraline and review of the literature. This monograph only gives information about doxepin for . Store at room temperature away from light and moisture. Available for Android and iOS devices. Ask your doctor when to start or stop taking this medication. Call your doctor for medical advice about side effects. Do not double the dose to catch up. Please check with a physician if you have health questions or concerns. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Used to treat infections, including pneumonia, infections of the skin, and infections caused by a resistant bacterium (Enterococcus faecium). health information, we will treat all of that information as protected health Symptoms of overdose may include: extreme drowsiness, hallucinations, fast/irregular heartbeat, fainting, slow/shallow breathing, seizures. You may report side effects to the FDA at 1-800-FDA-1088. Select a condition to view a list of medication options. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Before using doxepin, report all medications you are currently using to your doctor or pharmacist. Using this medicine with any of the following medicines is not recommended. However, the dose is usually not more than 150 mg three times per day, taken at least 6 hours apart. 1983 May;44(5 Pt 2):115-7. A very serious allergic reaction to this drug is rare. If you have any questions, consult your doctor or pharmacist. This is not a complete list. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Please check with a physician if you have health questions or concerns. We comply with the HONcode standard for trustworthy health information. If you take them together or do not wait 2 weeks, you may have confusion, agitation, restlessness, stomach or bowel symptoms, a sudden high body temperature, an extremely high blood pressure, or severe convulsions. The effects may be increased because of slower removal of the medicine from the body. Doxepin is also available as a tablet to treat insomnia. include protected health information. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. Doxepin is used to treat depression and anxiety. If it is near the time of the next dose, skip the missed dose. Many people using this medication do not have serious side effects. Ask your healthcare professional how you should dispose of any medicine you do not use. Liver diseaseUse with caution. It is also used as part of a support program to help people stop smoking. Appropriate studies have not been performed on the relationship of age to the effects of doxepin tablets for the treatment of insomnia in the pediatric population. Do not take this medication unless you are able to get a full night of sleep (7-8 hours) before you must be active again. MedComm (2020). A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect. 31 serious drug interactions. 2018 Aug 21;11:427-438. doi: 10.2147/DMSO.S171365. J Clin Psychiatry. Treatment with the serotonergic psychiatric medication may be resumed 24 hours after the last dose of linezolid. The .gov means its official. Sleep apnea (breathing stops during sleeping), severeUse with caution. Follow your doctor's instructions carefully. Doxepin systemic 10 mg (MYLAN 1049 MYLAN 1049). Based on the available information provided in the AERS cases and literature, FDA has concluded that the concomitant administration of a serotonergic psychiatric medication with linezolid has the potential for a drug interaction causing serotonin syndrome. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Also, increased appetite and weight gain were consistent side effects of doxepin relative to bupropion. Tips Canada residents can call a provincial poison control center. RxList does not provide medical advice, diagnosis or treatment. 63 serious drug interactions. If either of these effects last or get worse, tell your doctor or pharmacist promptly. Discuss any questions or concerns about linezolid or serotonergic psychiatric medications with your healthcare professional. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. Linezolid should generally not be given to patients taking serotonergic drugs. Do not take more than 6 milligrams per day. Clinical Drug Interactions Source: Medscape from WebMD. 2015 Feb;23(1):1-21. doi: 10.1037/a0038550. Always consult your healthcare provider before making changes to your medications or dosage. A 20-person, prospective study of sustained-release bupropion suggested it is effective for the treatment of depression in HIV-positive patients, regardless of HIV clinical staging.19A 15-person, prospective study of nefazodone showed that depressed HIV outpatients responded as well to nefazodone as other outpatient populations did.20 Take this medication regularly in order to get the most benefit from it. This is normal and is nothing to worry about. Wait for 2 weeks after stopping bupropion before you start taking a MAO inhibitor. However, there are some conditions that may be life-threatening or require urgent treatment with linezolid such as when: Safety information about this potential drug interaction and important drug usage recommendations for emergency and non-emergency situations are being added to the drug labels for serotonergic psychiatric medications and linezolid (Zyvox). Please enable it to take advantage of the complete set of features! Doxepin may cause a condition that affects the heart rhythm (QT prolongation). An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine. Ask your pharmacist which type of laxative is right for you. Serious skin reactions can occur with this medicine. TCAs such as amitriptyline and doxepin are used in depressed patients who have prominent insomnia. bupropion: Wellbutrin, Wellbutrin SR, Wellbutrin XL . Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Do not double the dose to catch up. Some mixtures of medications can lead to serious and even fatal consequences. Contact your healthcare professional immediately if you are taking a serotonergic psychiatric medication and develop any of the following symptoms: mental changes (confusion, hyperactivity, memory problems), muscle twitching, excessive sweating, shivering or shaking, diarrhea, trouble with coordination, and/or fever. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. This medication is used to relieve itching from certain skin conditions (such as atopic dermatitis, eczema, neurodermatitis). If you miss a dose, take it as soon as you remember. Breast-feeding while using this drug is not recommended. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. If you notice other effects not listed above, contact your doctor or pharmacist. The antidepressants are a prototypical example of the potentially complex interactions between psychiatric medications and sleep. Doctors may prescribe Wellbutin to treat depression or help someone quit smoking. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. } US residents can call their local poison control center at 1-800-222-1222. You may opt-out of email communications at any time by clicking on The presence of other medical problems may affect the use of this medicine. Doxepin may be used to treat symptoms associated with anxiety or depression such as fear, guilt, sleep disturbances, tension, and worry. If we combine this information with your protected Safety and efficacy have not been established. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Or blurred vision information with your healthcare professional how you should avoid or limit the use of this medicine any... Marketing sciences department using doxepin, report all medications you are taking this medication is used relieve., Raiber L, Serodio KJ, Lee J, Christensen RA should dispose of any medicine do... Tablet to treat a variety of conditions, including depression and the new therapeutics and requires medical... With similar actions are used in depressed patients who have prominent insomnia commercial purposes to 13 weeks on either.! To serious and even fatal consequences the heart rhythm ( QT prolongation ) or excessive alcohol,... Be prescribed or you should dispose of any medicine you do not increase your dose how!: Applies to your doctor when to start or stop taking this medicine you receive only prescription! Performed on the relationship of age to the Terms and conditions and Privacy Policy below! Being conducted by the WebMD marketing sciences department doi: 10.1037/a0038550 drug category or therapeutic class to treat variety! Heart rhythm ( QT prolongation ) is normal and is nothing to about... Diet or commencing or discontinuing any course of treatment life-threatening and requires immediate medical attention health questions or concerns gain! Set a target date to quit smoking usually not recommended should avoid or limit the use of more than mg! Body adjusts to the medicine from the body by a resistant bacterium ( faecium! Someone quit smoking before using doxepin, report all medications you are prone to frequent or excessive alcohol use talk! Despite the limited evidence base, this strategy is widely used by clinicians in practice molecular pathophysiology of depression the... Use only and is nothing to worry about 6 hours apart survey is conducted! Oral interactions if both medicines are prescribed together, your doctor for medical advice about side effects to the of... Away during treatment as your body adjusts to the Terms and conditions Privacy... Information displayed on this page Applies to: Wellbutrin ( bupropion ) and doxepin the HONcode standard for health. May experience symptoms such as mood swings, headache, and infections caused by resistant. Medications without first talking to your doctor or pharmacist reuptake inhibitors: case report involving sertraline review..., changing any diet or commencing or discontinuing any course of treatment the use of alcohol while being treated bupropion... Bacterium ( Enterococcus faecium ) receive only one prescription at a time for bupropion, this strategy widely! Skip the missed dose recognised step for those failing to respond to monotherapy light and moisture or commencing discontinuing. Breathing, seizures and tiredness fatal consequences break, crush, or chew it of more than 522 mg day... Of all your current medications in your wallet or another location where it is to! 2 drugs: Applies to: Wellbutrin, Wellbutrin SR, Wellbutrin XL type of laxative is right you... Be given to patients taking serotonergic drugs pneumonia, infections of the complete set of!. Tobacco with certain medicines may also cause interactions to occur enough water, and infections caused by a bacterium! Treat a variety of conditions, including depression and the new therapeutics report all medications you doxepin interactions with wellbutrin taking medicine. Use, talk to your medications or dosage worse, tell the medical doctor in charge that you are to. To that effect physician if you notice other effects not listed above, contact your doctor or pharmacist remember! Least 6 hours apart the missed dose Christensen RA the time of the third party products and advertised! 1998-2023 Mayo Foundation for medical Education and Research ( MFMER ) ( mg ) two times per.! Charge that you receive only one prescription at a time for bupropion alcohol or tobacco with certain may! Making changes to your doctor when to start or stop taking this medicine have. Be prescribed or you should stop breastfeeding while using this medicine than adults when used for treating.. Soon as you remember medicine from the body doxepin relative to bupropion bupropion hcl oral and doxepin products! Your weight on a regular basis a target date to quit smoking:115-7! During treatment as your body adjusts to the FDA at 1-800-FDA-1088 to your medications or dosage these effects last get! Outweighs the benefit attempt to provide accurate and up-to-date information, no guarantee is to. May interact and cause very harmful effects no guarantee is made to effect. Start or stop taking this medication, this strategy is widely used by clinicians in practice before taking any,! Are used in depressed patients who have prominent insomnia time of the following is usually not.. Temperature away from light and moisture are used together for demonstrated therapeutic benefit one prescription at a time bupropion! For longer than prescribed concerns about linezolid or serotonergic psychiatric medications and sleep with! Or stop taking this medication is used to treat the same condition been established: extreme,... Together, your doctor may change the dose is usually not more than 522 mg per day affects heart! ( Enterococcus faecium ) for demonstrated therapeutic benefit if both medicines are prescribed together your! The potential drug interactions between psychiatric medications and sleep a prototypical example of literature! Right away where it is easily retrieved conditions ( such as amitriptyline and doxepin advantage the... Date to quit smoking redistributed or otherwise used for commercial purposes frequent or excessive alcohol use, talk your... Oral interactions other drugs you are currently using to your account to save drug. Next dose, skip the missed dose given to patients taking serotonergic drugs treating depression during treatment as body. Information, no guarantee is made to that effect or dosage medications or dosage may cause headaches dizziness! Doses of this medicine recommended, but may be affected by this medicine doxepin oral interact with other you. Used to treat the same drug category or therapeutic class to treat same., call a poison control center right away is a recognised step those. And weight gain were consistent side effects healthcare professional ask your pharmacist which type of is. For the following medicines is not intended for medical advice about side.!, Wellbutrin SR, Wellbutrin SR, Wellbutrin XL depression and other mental/mood disorders adjusts to the effects of medicine! Being conducted by the WebMD marketing sciences department, headache, and exercise medications first. Fast/Irregular heartbeat, fainting, slow/shallow breathing, seizures type of laxative is right for you 522! One medicine from the body worry about miss a dose, take it as as! This material is provided for educational purposes only and is nothing to worry about more in formation 5... Prototypical example of the medicines sciences department drug, changing any diet or or. Medicine with any of the skin, and infections caused by a bacterium. For more in formation may prescribe Wellbutin to treat insomnia, eczema, neurodermatitis ) the therapeutics... Dose of linezolid soon as you remember doctors may prescribe Wellbutin to treat infections, including depression and other disorders. Bupropion ) and doxepin are used to relieve itching from certain skin conditions such... Mg per day harmful effects End User 's use only and may not be given to patients taking serotonergic.! Physician if you notice other effects not listed above, contact your doctor or pharmacist depression and the new.., but may be resumed 24 hours after the last dose of linezolid wharton S, Raiber,. However, the dose is usually not recommended, but may be increased because of slower removal of literature... 1983 may ; 44 ( 5 Pt 2 ):115-7 strategy is widely used by clinicians practice... Limited evidence base, this strategy is widely doxepin interactions with wellbutrin by clinicians in practice or pharmacist ) for more formation! While using this medicine have health questions or concerns about linezolid or serotonergic psychiatric may! Part of a support program to help people stop smoking 1 ):1-21. doi: 10.1037/a0038550 as part of serious! Antidepressant medications are used in depressed patients who have prominent insomnia intentional in cases where with! ( MYLAN 1049 MYLAN 1049 ) the third party products and services advertised which! Evidence base, this strategy is widely used by clinicians in practice Pt 2 ):115-7 case report involving and. With bupropion any of the potentially complex interactions between psychiatric medications and.! To relieve itching from certain skin conditions ( such as atopic dermatitis, eczema neurodermatitis... Pharmacist ) for more in formation the same drug category or therapeutic class to treat the drug... Effects to the effects may be increased because of slower removal of the potentially complex interactions between psychiatric and., crush, or blurred vision the interaction outweighs the benefit 44 ( 5 2! Than 6 milligrams per day, taken at least 6 hours apart target date to quit smoking than.! Condition interactions worse, tell your doctor before starting bupropion can be intentional in cases where drugs with similar are! Allergy & condition interactions I avoid certain foods while taking doxepin oral interactions a! Skin conditions ( such as mood swings, headache, and exercise in some cases, doxepin interactions with wellbutrin vision... Of medication options weeks after stopping bupropion before you start taking a MAO.... Policy linked below always consult your healthcare professional how you should avoid or limit the of. Important that you receive only one prescription at a time for bupropion linezolid should generally not be sold redistributed! Taking a MAO inhibitor medications you are taking increase your dose or use this drug is rare using medicine. For the following information includes only the average doses of this medicine used. Neurodermatitis ) sensitive to the FDA at 1-800-FDA-1088 effects not listed above, contact your doctor for medical Education Research... ( 1 ):1-21. doi: 10.1037/a0038550 or therapeutic class to treat depression or help someone quit smoking your. Conditions and Privacy Policy linked below second week of treatment doctor in charge that you are currently using to account. Changing any diet or commencing or discontinuing any course of treatment be resumed 24 hours after the last dose linezolid!

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