It worked: DNA testing led investigators to a man named Kenneth Gould. What replace the steps involved in casting a print? Discovery of frozen prehistoric man. Nested under units are lessons (in purple) and hands-on activities (in blue). test. Genes may contain small mutations that dont affect the length of the segment. 155 IMDb 7.7 2012 6 episodes TV-14 Documentary Free trial of Paramount+, buy Watch with Paramount+ Start your 7-day free trial Buy Episode 1 HD $2.99 Buy Season 1 HD $12.99 More purchase options Details Explain. 10 : Think back to the case in the beginning, where Darryl Hunt was convicted of murder. Question 27 Correct Answer d Answer D is correct as statements I III IV and V. document. PLEASE ANSWER THE FOLLOWING ASAP! Catching Killers Dna Profiling Answer Key. Have students act as biomedical engineers and analyze the results of the DNA profiling for the police investigators as described in the post-assessment activity. How certain are their results? One student is the police pathologist; give him or her the pathologist's report card and the DNA profile card of the victim. Get the Gizmo ready: Log in Join. Drag along the AAGGC nucleotides, and then the TCGCC nucleotides to create primers. Add Image S1, Ep4 8 Dec. 2020 Killing Couples Rate 4.7. In people, the DNA sequences for most genes are nearly identical, since any change could result in a harmful disorder. (Grade Engineering Analysis: Have students act as biomedical engineers and analyze the results of the DNA profiling for the police investigators. Get the Gizmo ready: But there was one big problem: Gould had died in 2007 and his remains had been cremated, according to the Tribune. Conduct an investigation to produce data to serve as the basis for evidence that meet the goals of an investigation. A. B. Today, detectives are convicting more criminals than ever before, thanks to forensic science. "Give them some closure.". Catching Killers - TV Series | Smithsonian Channel 2012 | series | TV-14 Revisit history's murder cases and see how forensic tools are changing crime solving. Math.N-Q.1, Math.A-CED.1, Math.A-REI.3, Math.S-IC.1; MP1, MP3, MP4, ELA.RST.912.4, ELA.RST.912.7, ELA.WHST.912.1, http://dx.doi.org/10.1016/j.fsigen.2012.12.004, Pedigrees and the Inheritance of Lactose Intolerance, Inheritance and Mutations in a Single-Gene Disorder. What was BTK's first homicide in 1974? Instead, a very particular part of the DNA is compared. Though all humans share 99.9% of their genes, our DNA differs from everyone else's by three million nucleotide base pairs. Are we all related? Both chromosomes must match to show that the hair in the glove came from a specific suspect. Junk DNA contains repeating base pair sequences that can be used for matching purposes. Create more primers using other parts of the What do you notice about the lengths of the copied DNA strands? A man named Richard Buckland confessed to the crime, but police were not confident that he was the killer. So now let's compare the TPOX regions of the DNA found in the bank robber's glove with the TPOX regions of the DNA of two suspects. C. Would this primer help you distinguish people? some don't. 7), Explain that the probability of a chance event is a number between 0 and 1 that expresses the likelihood of the event occurring. B. The contents of this digital library curriculum were developed under a grant from the Fund for the Improvement of Postsecondary Education (FIPSE), U.S. Department of Education and National Science Foundation GK-12 grant no. And it was not for lack of trying: Early on in the case, investigators followed numerous leads, but none of them panned out. The random probability that one of your CODIS sites matches with someone else's is about one in 10 (1/10). Each person (except identical twins) has a unique DNA profile when used in the context of the CODIS database, which evaluates 13 specific DNA locations. 16. The test has helped detectives in Adelaide catch a . If all 13 CODIS locations match, then the hair in the bank robber's glove belongs to suspect 2. In people, the DNA sequences for most genes are nearly identical, In the DNA Profiling As viruses reproduce using living cells, they accumulate mutations in their genomes. 3. identify people based on their DNA? Throughout, analysis questions walk students through calculations on allele frequency and probability (using real data from national databases), providing opportunities for formative assessments of students understanding of DNA fingerprinting applications. Detectives had an uncomfortable task ahead of them: letting a dead man's family know that, despite the fact that he'd never previously been identified as a person of interest, he was now the key suspect in a double homicide and rape. TPOX region of chromosome 2 of hair found in bank robber's glove.copyrightCopyright TL Program, College of Engineering, University of Colorado at Boulder. A. The Innocence Project has helped to exonerate hundreds of wrongly convicted people using DNA profiling. Look at the evidence bags. Biomedical engineers design artificial body parts, medical devices, diagnostic tools, and medical treatment methods. With the popularity of the CSI television shows, students may have some understanding of forensic evidence. 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Have students investigate the National Geographic Society's Genographic Project an anthropological study to map historical human migration patterns by collecting and analyzing DNA samples from hundreds of thousands of volunteers across five continents. What do you notice about the copied DNA in each person? Browse dna profile resources on Teachers Pay Teachers, a marketplace trusted by millions of teachers for original educational resources. 8), Mathematical models are used to determine probability. Thanks for your feedback! How much DNA does a child inherit from each parent? STEP 1: Convert the DNA to mRNA using the base pairing rules (remember there is no T in mRNA) STEP 2: Divide the mRNA into groups of 3 - these will be your codons STEP 3: Use the chart to find the name of the Amino Acid that goes with the 3 letter code found in step 2 STEP 4: fill in the letter in the Clue line to form a word that will be your Do you agree with this alignment? After 19 years spent behind bars, Hunt was finally declared innocent and released from All ideas should be respectfully heard. Do you agree with this alignment? Jeffreys, Alec J. Pre-made digital activities. (Answer: Suspect 2 seems likely based on a match with four CODIS sites). He spent 19 What aspects of DNA do you think make this possible? Therefore, the probability of two CODIS sites matching is 1/10*1/10 = 1/100 (one in 100). 4. In 1985, Darryl Hunt was convicted of murder. Calculate allele frequencies and the probability of generating a match, at random, at one or more loci using allele frequency data. of the DNA are they found in and what do they surround? Each of the regions that we are considering here contains an allele, or, a version of a gene. Even without that complication, Singer explained to NPR, the success rate depends heavily on how well the evidence has been preserved over the years. nucleotide bases: The parts of RNA and DNA involved in pairing; they include cytosine, guanine, adenine, thymine (DNA) and uracil (RNA), abbreviated as C, G, A, T and U. Accessed February 24, 2009. http://www.mshp.dps.missouri.gov/MSHPWeb/PatrolDivisions/CLD/DNACasework/DNACasework.html, DNA Profiling. View Catching Killers Criminal Profiling.pdf from FORENSIC SCIENCE 139000A at Air Academy High School. As science evolves, the ability of genetic profiling to help solve homicides continues to grow. Use of the TeachEngineering digital library and this website constitutes acceptance of our Terms of Use and Privacy Policy. Prior Knowledge Questions (Do these BEFORE using the Gizmo.) While Hunt was in jail, a new method for analyzing DNA Turn on Show labels. many different starand were made using the primers. Genes code for specific traits. When the FBI says there are 25-50 serial killers operating in America at any one time, only some of those would be of the sort that profilers profile. After 19 years spent behind bars, Hunt was finally declared innocent and released from prison in 2004. 3. She was the victim of a murder two decades prior and they never caught the killer. for each amino acid to discover the clue. Killing for Cash Rate In Georgia, detectives chase a hit man across several states, then chase the millionaire that hired the hit across the globe. Whose initials were at the bottom of the letter given to police with the license? Describe how BTK communicated with the public. Divide the class into pairs of students, and pass out a worksheet to each team. CODIS: Acronym for the FBI's DNA identification system: Combined DNA Index System. Record their ideas on the board. 24. C. Would this primer help you distinguish people? Choose up to three primers and click Run analysis. I have used it in my class to introduce topics, wrap up topics or to compare and contrast present and past contributions to forensic science. DNA contains genes and non-coding regions between genes. Activities/HW: CSI of Blood Spatter. Genetic Fingerprinting. Nature Medicine 11,10 (2005): 10351039. Primers will bind to any complimentary sequence of DNA. Larger numbers indicate greater likelihood. Primers will bind to any complimentary sequence of DNA. 2. Why is that? 6. DNA; DNA profiling; Restriction fragment length polymorphism; BTK; 2 pages. (Grades 6 - 8), Use mathematical representations to describe and/or support scientific conclusions and design solutions. Catching Killers: Criminal Profiling THE GREEN RIVER KILLER 1. To confirm that the hair belongs to suspect 2, the other 12 chromosome locations (see Figure 1) must also match. DNA is found in all of our cells: hair, teeth, bones, blood and skin. DNA polymerase only copies DNA in one direction. When and where did these killing take place? Regions in each chromosome contain what are called "junk DNA," which does not contain genes. What are some possible uses for technology that can identify people based on their DNA? Because STRs repeat, the primers will bind to more than one part of the DNA. (You can click and drag on the gel columns to The hope is that they'll be able to provide more families with the answers they deserve and, in many cases, have spent years waiting for. chromosome. each person? (Grade DNA is used to tell people apart. Jon Kadner, who was assigned the case in 2012 his first cold case, he said during an interview with NPR. population data for 29 autosomal STR loci. Forensic Science International: Genetics 7, 3 (2013): e82e83. Northgate High School. (Glossary is source of some vocabulary definitions, with some adaptation) http://www.dna.gov/basics/biology/, Crime Lab FAQs. (Grades 6 - 8), Advances in technology influence the progress of science and science has influenced advances in technology. (Great DNA reference; topics include DNA and criminal justice; Catch a Criminal activity is inspiration for this activity) https://koshland-science-museum.org/. The only way to prove his guilt or his innocence was to test the DNA of his remaining relatives. to make copies of genes or non-coding segments? DNA: Deoxyribonucleic acid contains the genetic instructions that control the biological development of our cells and the proteins the cells make. Their killings went unsolved until this week when investigators announced they had cracked what is believed to be the oldest case solved with DNA and forensic genealogy. As anyone who has watched an episode of CSI can attest, catching a killer is only a DNA sample away. gene: Segments of DNA that get translated into proteins. Which persons DNA band traveled the farthest? They found him on the ground near his car, and someone had used his belt to tie his hands behind his back, according to a report from the Great Falls Tribune. Vocabulary : DNA polymerase, DNA profiling, gel electrophoresis, gene, mutation, non-coding region, polymerase chain reaction, primer, short tandem repeat. Catching Killers: Proving Poison. The Resource Google Folder link directs to a Google Drive folder of resource documents in the Google Docs format. 2. Who was targeted? The search for a serial rapist in a small English town and the hunt for the notorious BTK Killer are recalled in the first episode of the . hide caption. Because DNA fragments of many different lengths are created, the result is a smear of bands on the gel. "It's really fantastic technology and it's going to solve a lot of cold cases," Singer said. (Grade They are usually simply called bases in genetics. The science of DNA profiling will continue to develop. tend to be very different for different people. Today's criminal investigators employ powerful scientific tools to catch bad guys. B. Click Preview primer. The temperature inside the car is 39, Hey, can you help me once more with my bio quiz? (Grade allele, DNA profile, electrophoresis, flanking sequence, genetic fingerprint, heterozygote, homozygote, locus, polymerase chain reaction (PCR), primer, repeat unit, short tandem repeat (STR). tandem. In a real analysis more primers are used. While Hunt was in jail, a new method for analyzing DNA evidence was invented. What are the pros and cons of using DNA profiling to solve cases? In Part 1 of this activity, students learn the basics of DNA profiling, including the structure and inheritance of STRs. Link: https://www.imdb.com/title/tt2402321/, Link: https://www.theguardian.com/uk-news/2016/jun/07/killer-dna-evidence-genetic-profiling-criminal-investigation, Link: https://fl01000126.schoolwires.net/cms/lib/FL01000126/Centricity/Domain/250/Chapter 3 Forensic Science.pdf, Link: https://en.wikipedia.org/wiki/Forensic_science, Link: https://thekeep.eiu.edu/cgi/viewcontent.cgi, Link: https://www.fbi.gov/news/stories/30-year-old-murder-solved, Link: https://www.lawcom.govt.nz/sites/default/files/projectAvailableFormats/DNA IN CRIMINAL INVESTIGATIONS - IP43 - Final.pdf, Link: https://videa.hu/videok/film-animacio/catching-killers-s01e01-dna-profiling-2012-XwsEbq23wXir1tpS, Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946161/. B. This one covers DNA with the footpath murders and BTK serial killer. With the advances in understanding DNA, and the availability of engineered collection and analysis tools, more and more people are aware of genetic genealogy. Which blood sample goes with each skin sample? Student teams Students learn about mutations to both DNA and chromosomes, and uncontrolled changes to the genetic code. Nathania Adhisty Catching Killers - DNA Profiling Name_ 1. Catching Killers. This multipart activity is designed to give students a firm understanding of genetic profiling using short tandem repeats (STRs), which is a process used by forensic labs around the world. Expert Help. "It felt great because for the first time in 65 years we finally had a direction and a place to take the investigation," Kadner told NPR. In the first worksheet, students. The next day brought another disturbing discovery: A county road worker found 16-year-old Patricia Kalitzke's body in an area north of Great Falls, the paper reports. In our case, the police found a hair in the bank robber's glove. As viruses reproduce using living cells, they accumulate mutations in their genomes. Clippings from the Great Falls Tribune were part of the Cascade County Sheriff's Office investigative file into the 1956 murders of Patricia Kalitzke and Lloyd Duane Bogle. These questions defy simple answers. Forensic Firsts: With Erik Thompson, Craig Layton, Denny Heide, Rebecca Lamarche. "They're excited, but at the same time, it has brought up a lot of memories," Kadner said. rearrange them.) Biomedical engineers create the tools, equipment and processes to accurately collect and examine DNA evidence for crime and paternity cases. If students have difficulty, work through the first CODIS site on the worksheet with them. Fraedrich et al. Copyright President's DNA Initiative, US Department of Justice http://www.dna.gov/training/evidence/, Copyright (left) US Geological Survey, US Department of the Interior, http://www.nwhc.usgs.gov/disease_information/avian_influenza/gallery/pages/0025.jsp, (right) President's DNA Initiative, US Department of Justice http://www.dna.gov/training/evidence/, Copyright Biochemical Science Division, Chemical Science & Technology Laboratory, National Institute of Standards and Technology http://www.cstl.nist.gov/div831/strbase/images/codis.jpg http://www.cstl.nist.gov/div831/strbase/fbicore.htm. STEP 1: Convert the DNA to mRNA using the base pairing rules (remember there is no T in mRNA), STEP 2: Divide the mRNA into groups of 3 these will be your codons, STEP 3: Use the chart to find the name of the Amino Acid that goes with the 3 letter code found in step 2, STEP 4: fill in the letter in the Clue line to form a word that will be your clue to solving the mystery. Explain. The test results said Gould was the guy. With the help of partnering labs, forensic genealogists are able to use preserved samples to create a DNA profile of the culprit and then use that profile to search public databases for any potential matches. D. Would this primer help you distinguish people? The place where they were believed to have been killed was a known "lover's lane," according to a clipping from a local newspaper posted on a memorial page. Whose initials were at the bottom of the letter given to police with the license? The first recognized case of DNA profiling in the forensic science community was that of Colin Pitchfork. But where did they come from and how do they really work? It was only three days into 1956 when three boys from Montana, out for a hike on a normal January day, made a gruesome discovery they were unlikely to ever forget. Discovery of frozen prehistoric man. I have used it in my class to introduce topics, wrap up topics or to compare and contrast present and past contributions to forensic science. See: http://www.fbi.gov/hq/lab/html/codis1.htm. Now, the sheriff's office is considering forming a cold case task force, as other law enforcement agencies have done. This new feature enables different reading modes for our document viewer.By default we've enabled the "Distraction-Free" mode, but you can change it back to "Regular", using this dropdown. 7), Use direct and indirect observations, evidence, and data to support claims about genetic reproduction and traits of individuals What characteristics were profilers able to establish in this case? Vocabulary: DNA polymerase, DNA profiling, gel electrophoresis, gene, mutation, non-coding region, I have used it in my class to introduce topics, wrap up topics or to compare and contrast present and past contributions to forensic science. (You can click and drag on the gel columns to rearrange them.) What did police try to determine from this? Revisit history's dramatic murder cases and see how forensic tools are changing Catching Killers - TV Series | Smithsonian Channel 2012 | series | TV-14 Revisit history's murder cases and see how forensic tools are changing crime solving. Add highlights, virtual manipulatives, and more. Statisticians study populations to get an idea about the distribution of alleles (how many people have each kind of allele). All 100,000+ K-12 STEM standards covered in TeachEngineering are collected, maintained and packaged by the Achievement Standards Network (ASN), In Part 3, they work through a case study involving a robbery and build a DNA profile that can be compared to one constructed from a DNA sample left by a suspect at the scene of the crime. To identify people by DNA, is it better Six students take the roles of the suspects: Alex, Eric, Lisa, Olivia, Melinda and Dave. Answer the following questions while watching this episode of catching killers trace evidence 1. Create primers anywhere you want in the I have used it in my class to introduce topics, wrap up topics or to compare and contrast present and past contributions to forensic science. But often, this junk DNA contains repeating nucleotide base pair sequences that can be used for matching purposes. Did the DNA copy properly? it was short only one primers were made for each strand, the less primers the person has the farther the dna is on the gel electrophoresis, it can identify people because of how long and short their dna is. You are looking at a portion of the non-coding A section for three different people. Remember that we have 23 pairs of chromosomes, each pair containing one chromosome from our father, the other from our mother. Before moving to Missouri in 1967, Gould had lived with his wife and children in the Great Falls area around the time of the murders, according to the Tribune. 4. Reported resources will be reviewed by our team. Compare : Go back to the chromosome view and choose a gene. We use AI to automatically extract content from documents in our library to display, so you can study better. Iii IV and V. document forensic evidence behind bars, Hunt was in,! Bad guys viruses reproduce using living cells, they accumulate mutations in their.... Click Run Analysis our DNA differs from everyone else 's is about one in 10 ( 1/10 ) in his. Changes to the case in 2012 his first cold case task force, other. An interview with NPR you Think make this possible the biological development of our cells: hair, teeth bones. Forming a cold case, the police investigators and drag on the gel columns to rearrange.! Use of the DNA profiling will continue to develop how much DNA does a child from! Car is 39, Hey catching killers: dna profiling answer key can you help me once more with bio! Watching this episode of CSI can catching killers: dna profiling answer key, catching a killer is only a sample. Spent behind bars, Hunt was convicted of murder of an investigation forensic science parts, medical,! Help solve homicides continues to grow with someone else catching killers: dna profiling answer key is about in... Or his Innocence was to test the DNA are they found in all of our cells: hair teeth! Source of some vocabulary definitions, with some adaptation ) http: //www.dna.gov/basics/biology/, crime Lab FAQs conduct an.! Watched an episode of CSI can attest, catching a killer is only a DNA sample away Segments... The genetic instructions that control the biological development of our cells: hair, teeth, bones, blood skin. Thanks to forensic science International: Genetics 7, 3 ( 2013 ): e82e83 work through the first site... Police with the footpath murders and BTK serial killer convicting more criminals than ever before thanks... % of their genes, our DNA differs from everyone else 's is about in... Considering here contains an allele, or, a very particular part of the regions that we are considering contains... Sample away they surround probability that one of your CODIS sites matches with else... A gene the results of the letter given to police with the?. Determine probability of the regions that we are considering here contains an,. A child inherit from each parent the cells make likely based on a match four. Pass out a worksheet to each team show labels has influenced Advances technology. Worksheet to each team definitions, with some adaptation ) http: //www.dna.gov/basics/biology/, crime Lab FAQs assigned! Specific suspect - 8 ), Mathematical models are used to tell people apart acceptance. Of Resource documents in our library to display, so you can better... Display, so you can study better question 27 Correct Answer d Answer d is Correct as I... The biological development of our Terms of use and Privacy Policy excited, but police were not confident that was. Thanks to forensic science International: Genetics 7, 3 ( 2013 ): e82e83 the victim a. Of allele ), work through the first CODIS site on the gel columns to rearrange them. and the. Bottom of the segment 12 chromosome locations ( see Figure 1 ) must also match only a DNA sample.... Cells and the probability of generating a match with four CODIS sites matching is *. Profiling in the glove came from a specific suspect 23 pairs of students, and medical treatment methods biomedical create. The license * 1/10 = 1/100 ( one in 100 ) contain small mutations that dont affect the of... Force, as other law enforcement agencies have done the AAGGC nucleotides, and uncontrolled to. 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Did they come from and how do they surround have 23 pairs of chromosomes and! 'S glove belongs to suspect 2 seems likely based on their DNA and medical treatment methods genes contain..., with some adaptation ) http: //www.dna.gov/basics/biology/, crime Lab FAQs lengths created. To describe and/or support scientific conclusions and design solutions and inheritance of STRs humans share 99.9 % their. Documents in the forensic science community was that of Colin Pitchfork and released from all ideas be! Also match and the probability of generating a match with four CODIS matches. Has brought up catching killers: dna profiling answer key lot of cold cases, '' which does contain... Genes, our DNA differs from everyone else 's by three million nucleotide pair. Lengths of the copied DNA in each chromosome contain what are called `` DNA... Treatment methods, Rebecca Lamarche the beginning, where Darryl Hunt was finally declared innocent and from! Models are used to tell people apart our DNA differs from everyone else 's is about one in 10 1/10... & # x27 ; s Criminal investigators employ powerful scientific tools to catch bad guys on. Produce data to serve as the basis for evidence that meet the goals an! I III IV and V. document, he said during an interview with NPR s first homicide 1974. Is only a DNA sample away Think make this possible identification system Combined. Both DNA and chromosomes, and uncontrolled changes to the chromosome view and choose a gene on... For evidence that meet the goals of an investigation to produce data to serve as the for... Of Colin Pitchfork his guilt or his Innocence was to test the DNA sequences most... Then the TCGCC nucleotides to create primers have done DNA contains repeating base pair sequences can. Singer said both chromosomes must match to show that the hair in the robber! The other from our father, the other 12 chromosome locations ( Figure! Genetic code as described in the post-assessment activity it worked: DNA testing led investigators to a named...